Silence by André Goffinet   The commentary by Popescu et al. expresses concern that gain-of-function research has gotten a bad rap. The commentary first notes that gain-of-function research describes a wide array of genetic methods, including the use of fluorescent proteins in basic research, the creation of mouse models for studying disease, and the creation...

  At Biosafety Now, our vision is a future free of lab-created pandemics. These may arise as a result of human error, which is exceedingly common in legitimate, regulated laboratories as catalogued by the American Biological Safety Association. If such an accident involves a highly transmissible pathogen, a pandemic may arise. Lab-created pandemics can arise from...

Artwork: La Promesse by André Goffinet Since the first rumblings about a possible lab leak in Wuhan, my position has been that it is as acceptable, and indeed as inevitable, for a non-scientist to be concerned about gain-of-function research of concern (GOFROC) as they are about climate change and nuclear conflict. But outsiders who choose...

    Domain expertise and monopoly of knowledge   In the debate about the origin of COVID-19, claims exist that only “domain experts” are qualified to comment; that the opinion of “outsiders” should be devalued, if not disregarded altogether. This is neither a new claim, nor unique to any specific scientific field. However, at the...

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